Clonidine-induced facilitation of baroreceptor reflex.
نویسندگان
چکیده
منابع مشابه
Baroreceptor reflex function.
THE IMPORTANCE of the baroreceptor reflex is to stabilize perfusion pressure in the face of disturbances of circulatory homeostasis. This is achieved by a number of neuronal (8, 29, 37, 48) and humoral (37, 45, 46) regulatory adjustments. These adjustments are initiated by a change in the pressure load at specialized pressure sensors located at the aortic arch and the carotid sinuses. Especiall...
متن کاملDiet-induced obesity severely impairs myelinated aortic baroreceptor reflex responses.
Diet-induced obesity (DIO) attenuates the arterial cardiac baroreceptor reflex, but the mechanisms and sites of action are unknown. This study tested the hypothesis that DIO impairs central aortic baroreceptor pathways. Normal chow control (CON) and high-fat-chow obesity-resistant (OR) and obesity-prone (OP) rats were anesthetized (inactin, 120 mg/kg) and underwent sinoaortic denervation. The c...
متن کاملRoles of Arterial Baroreceptor Reflex During Bezold-Jarisch Reflex
Among the many cardiopulmonary reflexes, this review specifically examines the roles of the arterial baroreflex during the Bezold-Jarisch reflex (BJR). Activation of cardiopulmonary vagal afferent C-fibers induces hypotension, bradycardia, and apnea, which are known collectively as the BJR; myocardial ischemia and infarction might induce the BJR. Arterial baroreflex has been established as an i...
متن کاملComparison in Conscious Rabbits of the Baroreceptor-Heart Rate Reflex Effects of Chronic Treatment with Rilmenidine, Moxonidine, and Clonidine
We investigated the effects of chronic subcutaneous treatment with centrally-acting antihypertensive agents moxonidine, rilmenidine, and clonidine on the baroreflex control of heart rate (HR) in conscious normotensive rabbits over 3 weeks. Infusions of phenylephrine and nitroprusside were performed at week 0 and at weeks 1 and 3 of treatment to determine mean arterial pressure (MAP)-HR barorefl...
متن کاملNonlinear analysis of the baroreceptor reflex system.
• The cardiovascular system is a complex mechanical, chemical, and hemodynamic system in which the variables are interrelated through a variety of feedback mechanisms. Of the various mechanisms that control cardiovascular function, the one that has been most thoroughly investigated is the baroreceptor reflex. The performance of the baroreceptor reflex has been studied previously in preparations...
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ژورنال
عنوان ژورنال: BMJ
سال: 1977
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.2.6090.802